Well-functioning cell mitochondria promote good health
California Agriculture 65(3):136-140. DOI: 10.3733/ca.v065n03p136.
Mitochondriol function can be directly linked to protection from certain chronic diseases and conditions, such as heart disease, diabetes, metabolic syndrome and chronic inflammation, as well as the aging processes. Mitochondria are central to normal glucose, amino acid and fatty acid metabolism, in addition to antioxidant modulation and virtually all aspects of cell turnover and maintenance. Nutrition plays an essential role in optimizing such functions. We describe strategies for the regulation of mitochondria, as well as metabolic strategies for dealing with the thousands of compounds in plants and animal tissues that are metabolically important. Many of these compounds function to signal the up- or downregulation of mitochondria or act as antioxidants.
W. Chowanadisai is Research Associate, UC Davis. C.L. Keen is Professor, Department of Nutrition, UC Davis. J. Liu is Professor, Graduate Center for Toxicology, University of Kentucky; R.B. Rucker is an Emeritus Professor, Department of Nutrition, UC Davis. E. Sharman is Research Specialist and Biochemist, Department of Neurology, UC Irvine; S.F. Shenoy is Senior Research Nutritionist, Pharmavite, Northridge, CA;
Robert M. Hackman, Research Nutritionist in the UC Davis Department of Nutrition, served as Guest Associate Editor for this article. We acknowledge the Vitamin Cases Consumer Settlement Fund (Contract No: 06-000427) from the State of California, which provides support for the UC Davis Center for Nutrition and Health Research, and additional support from Project 985, Jiaotong University, Xian, China; Mars, Incorporated; and Mitsubishi Gas Chemical Company, Inc.